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Published: Wed, December 28, 2016
World | By Tasha Manning

Histopathology: PATHOLOGY OF THE INTESTINE DELGADO AND COLON

Histopathology: PATHOLOGY OF THE INTESTINE DELGADO AND COLON

The duodenal mucosa is distinguished from that of the rest of the small intestine by containing mucoproductive submucosal glands known as brunner glands.

The complications of meckel diverticulum are peptic ulcers, which, if they pierce the cavity Free abdominal produce peritonitis; Can produce digestive haemorrhages, symptoms similar to those of acute appendicitis.

COLON:

CROHN'S DISEASE

Etiology is unknown, it is most likely that the disease is a result of a genetically determined dysregulation of the intestinal immune response, which causes an overactive inflammatory response to the presence of common bacterial antigen lumens that, in susceptible individuals causing no damage Some can affect any part of the digestive tract.

Injuries can have segmental distribution; That is, there may be an affected area, then there is healthy mucosa and then an area of ​​injured mucosa reappears. This disease has a preference for the right side and the small intestine and has transmural affection; That is, it affects the mucosa, submucosa, muscular and adventitia.

  • Rectorragia Abnormal sigmoidoscopy (presence of fistulas, fissures, ulcers)
  • Abdominal pain usually on the right side
  • Reduced intestinal lumen
  • Thickening of the wall.
Fissure formation / B> Abundant adipose tissue wrapping the intestine.

The middle portion shows a thickened wall and Mucosa has lost the usual folds and presents deep figures.

It is an inflammatory disease of etiology

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Unknown disease that affects the colon, just as crohn's disease appears to be due to dysregulation of the colon's immune response.

Continuous lesions from the rectum and usually limited to the colon, B> hemicolon left but is also seen in the ileum and cecal apencice, affects mucosa and submucosa except in severe cases where there may be transmural affection. Patients with ulcerative colitis have a higher risk of developing colon cancer than the general population.

Diarrhea Abnormal sigmoidoscopy. Red, congestive, granular and friable mucosa

  • >
  • Plasma cells and lymphocytes in the lamina propria
  • Neutrophilic infiltrate in the epithelium and crypt lumen when the disease is active.
  • Regenerative changes in the mucosa that can produce glandular atrophy and fibrosis.
Neutrophilic abscesses in the glandular lights of lieberkuhn's cryptists.

The mucosal surface of the colon is partially covered by a yellowish greenish exudate.

  • Necrotic and fibrinopurulent remains. Mycobacterium tuberculosis is the causative agent of most cases of intestinal tuberculosis.
  • Neutrophilic inflammatory infiltrate Thanks to pasteurisation of milk, M. bovis infection is uncommon. The bacillus enters the intestine through ingestion of sputum or contaminated food. The infection can develop in any organ of the digestive tract; However, the most frequently affected segment is the ileocecal region.

  • Ovarian ulcers
  • Extensive fibrosis affecting All layers of the intestine.
  • Stenosis
  • Adherence between handles

    • Well-formed granulomas with central caseous necrosis located in the peyer's plaques
    • Diffuse infiltrate consisting of vacuolated histiocytes In immunodeficients).

    INTESTINAL ISCHEMIC DISEASE

    Intestinal ischemic disease occurs as Due to the inadequate flow of oxygenated blood to the intestines, is a serious disease with more than 50% and is observed mainly in elderly, hypertensive, diabetic, with atherosclerosis. Atherosclerotic aorta complicated with ulcerations and calcifications may give rise to embolus or produce local thrombosis at the level of the mesenteric artery. Arterial thrombi produce large infarcts and occlusion of the terminal arteries produces local infarcts. Large infarcts Or large vessels affect the entire wall (transmural infarcts) and the focal mucosa and submucosa (murals) are usually

    The mucosal and mural infarction shows an edematous and hemorrhagic mucosa, necrosis of the mucosa and / or submucosa and a lalmina of its own denuded or exposed by detachment of the affected mucosa and submucosa.

Hemodynamic Iinestabilization

The small intestine between red and gray contrasts with the pale pink color of the normal bowel.

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