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Published: Wed, March 22, 2017
World | By Tasha Manning

Decreased Ovarian Reserve (DOR) - Gynecology and Obstetrics - Merck Manuals Professional Edition

Decreased Ovarian Reserve (DOR) - Gynecology and Obstetrics - Merck Manuals Professional Edition

11515 Sangrado Dr, Bakersfield, CA 93311 | Zillow
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Follicle-stimulating hormone (FSH) and estradiol levels for screening

> Antimüllerian hormone (AMH) level and antral follicle count (AFC)

Testing for decreased ovarian reserve is considered for women who They have responded poorly to treatments such as ovarian stimulation with exogenous gonadotropins

The AFC is the total number of follicles that measure 2 to 10 mm (mean diameter) in both ovaries during the early follicular phase; AFC is determined by observation during transvaginal ultrasonography. If AFC is low (3 to 10), pregnancy after IVF is less likely.

Decreased ovarian reserve can also be measured using the clomiphene citrate challenge test; However, it is less reliable. For this test, the woman is given clomiphene 100 mg po once / day on days 5 to 9 of the menstrual cycle; Then FSH and estradiol levels are measured again. A dramatic increase in FSH and estradiol levels from day 3 to day 10 of the cycle indicates decreased reserve.

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