Published: Thu, May 18, 2017
World | By Tasha Manning

New genes linked to endometriosis

New genes linked to endometriosis

Women who have one of two genetic variants may be more likely to develop endometriosis, according to a recent study that may give clues as to the causes of this mysterious condition.

Researchers say this is the first study to show a genetic link in the disorder that affects 6 to 10 percent of women of childbearing age.

Endometriosis is growth Abnormal cells similar to those found inside the uterus in other areas of the body, such as the ovaries and intestine. These growths could lead to inflammation, pelvic pain, painful menstrual periods and infertility for some women. "We have known for some time that endometriosis is congenital, but so far we have been unable to find any robust genetic variations that Influence a woman's risk of developing the disease, "Krina Zondervan, a research fellow at Wellcome Trust at the University of Oxford in England, says in a press release.

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" Our study is a Because it offers the first solid evidence that variations in DNA make some women more likely to develop endometriosis, "says Zondervan. "Now we need to understand the effect of these variations on the body's cells and molecules." In the study, published in Nature Genetics, researchers compared the genes of 5,586 women Who had endometriosis with 9,331 women who did not have it.

The results showed that women who had two distinct genetic variations were more likely to develop endometriosis.

Researchers say that if further studies confirm these two genetic variants as key players in the development of endometriosis, this could lead to better ways to diagnose and treat the disease.

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